CASE 3261 Published on 21.11.2005
0

Multiple gastrointestinal stromal tumors (GISTs) of the small and large intestine

Section

Abdominal imaging

Case Type

Clinical Cases

Authors

Sidiropoulou M, Giannopoulos T, Anastasiadou K, Petridis A, Palladas P

Connected authors
Patient

60 years, female

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Clinical History
A 60-year-old woman visited our hospital’s emergency room complaining about vague abdominal pain. A CT scan was obtained, which revealed the presence of multiple small and large bowel masses which demonstrated an endoenteric, exoenteric growth pattern and mural thickening. All tumors were surgically resected.
Imaging Findings
A 60-year-old woman visited our hospital’s emergency room complaining about vague abdominal pain. Her medical history was unremarkable. She had no history of alcohol or drug abuse, she took no medications and she did not have any known allergies. A CT which was taken revealed the presence of multiple small and large bowel masses which demonstrated an endoenteric, exoenteric growth pattern and mural thickening. These lesions were homogenous, isodense to muscle and well-defined. Their size varied and, in some cases, exceeded 5 cm. Some of these tumors protruded into the intestinal lumen and displaced other loops. All tumors were surgically resected. The histological features and immunohistochemical staining characteristics were consistent with those of multiple gastrointestinal stromal tumors. The patient underwent therapy of imatinib mesylate (Gleevec).
Differential Diagnosis List
Multiple gastrointestinal stromal tumors (GISTs) of the small and large intestine.
Final Diagnosis
Multiple gastrointestinal stromal tumors (GISTs) of the small and large intestine.
Case information
URL: https://eurorad.org/case/3261
DOI: 10.1594/EURORAD/CASE.3261
ISSN: 1563-4086
Figure 1

Figura 1

Figura 1
A CT image showing a homogeneous, isodense to muscle, well-defined exoenteric mass (indicated by an arrow) arising from the transverse colon.
Figura 1
A CT image showing the same intestinal tumor compressing an adjacent jejunal loop.
Figure 2

Figura 2

Figura 2
A CT scan showing an endoenteric ileal mass nearly obliterating the loop’s lumen (indicated by an arrow).
Figure 3

Figura 3

Figura 3
A CT scan showing an oval homogeneous mass of the small intestine (diameter: 5 cm), ventral to the descending colon.
Figure 4

Figura 4

Figura 4
A CT scan depicting two lesions. The former mass is oval, homogeneous with a diameter >5 cm and the latter presents significant mural thickening.
Figura 4
A CT scan showing the latter lesion almost occluding the loop’s lumen and demonstrating a large exoenteric component which displaces an other loop.
Figura 4
A CT scan showing the previously mentioned mass having a vertical diameter of 6 cm. Note the string pattern of the contrast medium.
Figure 5

Figura 5

Figura 5
A CT scan depicting an ovoid homogeneous exoenteric mass in the right lower quadrant.
Figure 6

Figura 6

Figura 6
A CT scan showing a mass (indicated by an arrow) protruding from ileal loops in the pelvis.
Figura 6
A CT image depicting the mass (indicated by an arrow) shown in Fig. 6a, which has a diameter of 8 cm and displaces the uterus ventrally.