Case 71
Nasopharyngeal carcinoma of the Regaud type
Author(s)
Lemort M, Leurquin M
Patient
male, 32 year(s)
Clinical History
Large tumour of the nasopharynx found after complaints
of persistant facial pain
Imaging Findings
This patient, a woodworker, was referred in our institution
for staging of a large rhinopharyngeal tumour discovered
after persistent pain following extraction of a right
superior molar tooth. A trigeminal neuralgy was already
diagnosed.
A MR examination is performed using following sequences :
T1w SE axial and frontal pre and post Gd DOTA, T2w SE axial.
Where is the posterior limit of the lesion ?
What about the masticator space ?
Is there any intracranial extension ?
How do you explain the high signal on the T2w images of
the mastoid cells ?
Discussion
Both the retropharyngeal spaces and the left prevertebral
space are involved.
The tumour infiltrates the masticator space with a
perineural extension around the V3 nerve up to Meckel's
cave.
The intracranial extension follows a perineural way
(V3 --> foramen ovale --> Meckel's cave) and a contiguous
way through the sphenoid sinus.
The hypersignal in the mastoid cells is caused by
middle-ear fluid resulting from Eustachian tube malfunction
(probably due to a tumour infiltration of the torus tubarii).
Diagnosis was confirmed by biopsy : nasopharyngeal epithelioma (Regaud type). This refers to an undifferenciated nasopharyngeal carcinoma with foci of cells from epithelial origin (ref.1-3).
The patient was only partially treated by chemo- and
radiotherapy because he was lost of follow-up.
Final Diagnosis
Undifferenciated nasopharyngeal carcinoma (Regaud type)
References
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[1]
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[2]
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[3]
Citation
Lemort M, Leurquin M (2000, Jan 17).
Nasopharyngeal carcinoma of the Regaud type, {Online}.
URL: http://www.eurorad.org/case.php?id=71