EURORAD ESR

Case 77

Midgut carcinoid tumor

Author(s)
AS Rangheard, C Dromain, A Loshkajian, R Sigal
 
Patient
female, 45 year(s)

Clinical History

flushes, diarrhea, palpitations and abdominal pain.

Imaging Findings

A 45-year old woman was admitted to the hospital with a 4 months history of flushing associated to diarrhea, palpitations and abdominal pain. The abdominal examination showed a nodular hepatomegaly. Biologically was found an urinary 5-HIAA excretion (normal ranged from 10 to 80 umol/24 h). An ultra-sonography and an abdominal computed tomography (CT) were performed. CT exploration : After administration of an oral contrast medium, a dual-phase helical CT was performed : before and after injection of a iodine contrast medium (100 ml).

Discussion

Carcinoid tumors arise from the bowel distal to the ligament of Treitz(1).Their typical manifestion is the carcinoid syndrome with flush,diarrhea and palpitations(3),associated to an urinary 5- HIAA excretion(2). Carcinoid tumors tend to metastasize to liver, bone and lung (1). Hepatic metastases are hypervascular: isodense relative to the liver, and become hyperdense after injection of a iodine contrast medium (1). The primary tumor is not always identified on CT examination because of its relatively small size(4).When it is seen, it appears as a soft tissue mass involving the bowel, or a focal bowel wall thickening. CT frequently reveals secondary mesentery changes as masses associated with radiating soft tissue strandS (1;4).

Final Diagnosis

midgut carcinoid tumor
 

MeSH

  1. Carcinoid Tumor [C04.557.470.200.025.200]
    A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)

References

Citation

AS Rangheard, C Dromain, A Loshkajian, R Sigal (2000, Apr 3).
Midgut carcinoid tumor, {Online}.
URL: http://www.eurorad.org/case.php?id=77
 
  • Figure 1
    Liver metastases
    a b  

    Tomodensitomètrie spiralée Coupe TDM axiale montrant de multiples lésions hépatiques de densité intermédiaire, certaines présentant un centre hypodense en rapport avec de la nécrose.

    Tomodensitomètrie spiralée Coupe TDM axiale après injection de produit de contraste iodé (temps précoce) révélant un important rehaussement des lésions hépatiques.

     
  • Figure 2
    Mesenteric mass
    a b  

    Tomodensitomètrie spiralée Coupe TDM axiale après contraste révélant une masse mésentérique avec des extensions radiaires. Pas d'adénomégalie, pas d'épanchement péritonéal.

    Tomodensitomètrie spiralée Mêmes éléments. Les extensions radiaires ne sont pas visibles sur cette coupe.

     
Figure 1

Liver metastases

Figure 1a
Tomodensitomètrie spiralée Coupe TDM axiale montrant de multiples lésions hépatiques de densité intermédiaire, certaines présentant un centre hypodense en rapport avec de la nécrose.
 
Figure 1b
Tomodensitomètrie spiralée Coupe TDM axiale après injection de produit de contraste iodé (temps précoce) révélant un important rehaussement des lésions hépatiques.
 
Figure 2

Mesenteric mass

Figure 2a
Tomodensitomètrie spiralée Coupe TDM axiale après contraste révélant une masse mésentérique avec des extensions radiaires. Pas d'adénomégalie, pas d'épanchement péritonéal.
 
Figure 2b
Tomodensitomètrie spiralée Mêmes éléments. Les extensions radiaires ne sont pas visibles sur cette coupe.
 
 
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