EURORAD ESR

Case 93

Squamous cell carcinoma of the floor of the mouth

Author(s)
R Sigal, AM Leridant, O Casiraghi
 
Patient
female, 47 year(s)

Clinical History

Imaging Findings

Recent appearance of left mandibulary pain, not resolving under current sedation. Physical examination revealed an ulcerative and infiltrative lesion of the anterior floor of the mouth, adherent to the gingiva. Biopsy disclosed a well differentiating, keratinizing squamous cell carcinoma CT and MR were obtained in the pre therapeutic workup.

Discussion

Squamous cell carcinoma of the oral cavity represent less than 1% of all tumors. They are due to alcohol and tobacco exposure. The diagnosis is suspected by the patient or a physician (dentist). Most often the histological diagnosis when the patient is referred for imaging workup. Imaging plays an essential for tumor mapping. It shows the relationship with the main supporting structures of the oral cavity : muscles of the floor of the mouth (mylohyoid, geniohyoid, anterior belly of digastic muscles) and tongue (genioglossus), and lingual pedicle. Imaging is particularly important to evaluate the bone. The cortical bone is seen at best on CT, with bone window setting. The medullary bone is evaluated on T1-weighted MR sequence. Normal medullary bone is displayed with high signal intensity. In case of tumor invasion, the medullary bone is replaced by low signal intensity areas. However, this finding is nonspecific and is also found in inflammatory and infectious condition, a frequent problem in this population with poor dental status.

Final Diagnosis

Squamous cell carcinoma of the floor of the mouth
 

MeSH

  1. Mouth Neoplasms [C04.588.443.591]
    Tumors or cancer of the MOUTH.

References

Citation

R Sigal, AM Leridant, O Casiraghi (2000, Jun 23).
Squamous cell carcinoma of the floor of the mouth, {Online}.
URL: http://www.eurorad.org/case.php?id=93
 
  • Figure 1
    Squamous cell carcinoma of the floor of the mouth: CT findings
    a b  

    Imaging discloses a midly enhancing lesion which abuts the cortex of the mandible.

    Same level as fig 1a, bone window setting. There is no evidence of lysis of the cortical bone of the horizontal branch of the mandible

     
  • Figure 2
    Squamous cell carcinoma of the floor of the mouth: MRfindings
    a b c  

    T1 Weighting, Same level as Image 1. The tumor (arrow) is displayed as a low signal intensity area. The medullary bone is normal

    T2 Weighting, Same level as Image 1. The lesion invades the genioglossus muscle

    T1 weighting, Gadolium injection, fat suppression. The lesion midly enhances with contrast

     
Figure 1

Squamous cell carcinoma of the floor of the mouth: CT findings

Figure 1a
Imaging discloses a midly enhancing lesion which abuts the cortex of the mandible.
 
Figure 1b
Same level as fig 1a, bone window setting. There is no evidence of lysis of the cortical bone of the horizontal branch of the mandible
 
Figure 2

Squamous cell carcinoma of the floor of the mouth: MRfindings

Figure 2a
T1 Weighting, Same level as Image 1. The tumor (arrow) is displayed as a low signal intensity area. The medullary bone is normal
 
Figure 2b
T2 Weighting, Same level as Image 1. The lesion invades the genioglossus muscle
 
Figure 2c
T1 weighting, Gadolium injection, fat suppression. The lesion midly enhances with contrast
 
 
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